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Chemical Information
Flash_Point 250.9±25.0 °C
Molecular_Formula C16H12O7
Density 1.6±0.1 g/cm3
Exact_Mass 316.058289
LogP 1.89
Boiling_Point 659.1±55.0 °C at 760 mmHg
Melting_Point 267ºC
Molecular_Weight 316.262
Vapour_Pressure 0.0±2.1 mmHg at 25°C
PSA 120.36000
Index_of_Refraction 1.727
Safe Information
HS_Code 2914509090
Product Information
Flash_Point 250.9±25.0 °C
Molecular_Formula C16H12O7
CAS_Number 520-11-6
Boiling_Point 659.1±55.0 °C at 760 mmHg
Common_Name Nepetin
Melting_Point 267ºC
Molecular_Weight 316.262
MSDS N/A
Density 1.6±0.1 g/cm3

6-METHOXYLUTEOLIN Basic information


Product Name:

Nepetin

 

Synonyms:

6-Methoxyluteolin; Eupafolin; NSC 122416; 3',4',5,7-Tetrahydroxy-6-methoxyflavone

 

CAS:

520-11-6

 

MF:

C16H12O7

 

MW:

316.26

 

Product Categories:

Tetra-substituted Flavones

 

6-METHOXYLUTEOLIN Chemical Properties


Melting point 

267°C

 

Boiling point 

659.1±55.0 °C(Predicted)

 

density 

1.605

 

Fp 

90

 

storage temp. 

2-8°C

 

solubility 

Soluble in methanol;

 

form 

powder

 

pka

6.48±0.40(Predicted)

 

color 

Yellow

 

Water Solubility 

slightly soluble in water

 

6-METHOXYLUTEOLIN Usage And Synthesis


Chemical Properties

Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the leaves of Artemisia argyi, the aerial part of the aerial part of A. syringae officinalis.

Uses

Nepetin can be anti-tumor, insecticide, anti-SARS virus, and antibacterial.

Biological Activity

Zelan flavonoid (6-Methoxyluteolin) is a natural flavonoid isolated from Eupatorium ballotaefolium HBK with potent anti-inflammatory activity. Nepetin inhibits IL-6, IL-8 and MCP-1 secretion in ARPE-19 cells with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively.

target

Calcium Channel | Histamine Receptor


Nepetin, 520-11-6 is a natural flavonoid isolated from Eupatorium ballotaefolium HBK and is known to have anti-tumor, insecticide, anti-SARS virus, and antibacterial properties. It is a yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents. It has a melting point of 267 degrees Celsius and a boiling point of 659.1 plus or minus 55.0 degrees Celsius, a density of 1.605, and a pKa of 6.48 plus or minus 0.40. It is slightly soluble in water and is derived from the leaves of Artemisia argyi, the aerial part of the aerial part of A. syringae officinalis.

 

Nepetin has many pharmacological properties, including anti-inflammatory and antifungal activities. It has been shown to inhibit IL-6, IL-8 and MCP-1 secretion in ARPE-19 cells with IC50 values of 4.43 μM, 3.42 μM and 4.17 μM, respectively. It also has a potential calcium channel blocking effect and is a histamine receptor antagonist.

 

Nepetin has a wide range of potential therapeutic applications, including the treatment of cancer, SARS virus, and other infectious diseases. It has also been investigated for its potential use in the prevention of cardiovascular diseases and in the treatment of Alzheimer's disease.

 

In addition to its medicinal uses, Nepetin can also be used as a food additive to enhance the flavor and color of food. It is also used as a dye in the production of cosmetics and other products.

 

related product:

3',4',5',5,6,7-HEXAMETHOXYFLAVONE CAS NO:29043-07-0

https://www.finetechchem.com/product/prod_detail/29043-07-0

 

3',4',5',6,7,8-HEXAMETHOXY-5-HYDROXYFLAVONE CAS NO:21187-73-5

 https://www.finetechchem.com/product/prod_detail/21187-73-5

 

SINENSETIN  CAS NO:2306-27-6

https://www.finetechchem.com/product/prod_detail/2306-27-6